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BOTOX® Cosmetic is a simple, nonsurgical physician and nurse administrated treatment that can temporarily smooth moderate to severe frown lines between the brows in people from 18 to 65 years of age. It is the only treatment of this type approved by the U.S. Food and Drug Administration (FDA).

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RESTYLANE was approved by the FDA in December 2003 for use as an injection to help correct moderate to severe facial wrinkles and faults, including the lines between the nose and the mouth of a person.

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Frequently Asked Questions about Botox:

What causes frown lines between the brows?

The lines that appear between your brows actually result from muscle movement and the passage of time.

Two muscles are largely responsible for frown lines between the brows.  When those muscles contract, they draw the brows together.  As skin becomes less elastic over time, repeated frowning can result in those moderate to severe lines between the brows.

Just what is Botox® Cosmetic?  Is it FDA approved?

It is a purified protein administered in a simple nonsurgical procedure that temporarily improves the appearance of moderate to severe frown lines between the brows in people aged 18 to 65.  During treatment, very low doses of Botox® Cosmetic are administered via a few tiny injections directly into the muscles that cause those stubborn lines between the brows.

What is the difference between Botox® Cosmetic and fillers?

Frown lines are caused by overactive facial muscles.  Fillers mask the wrinkle by adding volume around the muscle with intradermal injections.  Botox® Cosmetic is the only product of its type that affects the muscles that cause these wrinkles.

What are the common side effects?

The most common side effects following injections of Botox® Cosmetic include headache, respiratory infection, flu syndrome, temporary eyelid droop, and nausea.

Have patients been happy with their results?

According to a recent survey of 204 dermatologists and plastic surgeons, Botox® Cosmetic has the highest satisfaction rating of all physician-administered treatments in 2003 and 2004.*  And for the past 3 years, Botox® Cosmetic was the most popular physician-administered cosmetic procedure in the United States (surgical and nonsurgical combined).†

How can I be sure I’m getting real Botox® Cosmetic?

Only licensed and trained healthcare professionals have the experience necessary to administer Botox® Cosmetic.  Allergan, Inc., the maker of Botox® Cosmetic, is the only source of  healthcare professionals to purchase the product, and each label has the “Allergan” hologram.
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How soon will I see a difference?  What kind of results can I expect?

You can expect to see results within days after your treatment.  The appearance of the area between your brows may continue to improve for up to a week.

By day 30 in a patient clinical study, 89% of patients judged the severity of their frown lines between their brows as moderate or better.

What is the treatment like?

Botox® Cosmetic treatment is quick and minimally invasive.  Your doctor makes a few tiny injections into the muscles that cause moderate to severe frown lines between your brows.

Your doctor will determine exactly where to administer the injections to achieve the best results.  No anesthesia is required, although he or she may choose to numb the area with a cold pack or anesthetic cream prior to injecting.  The entire procedure takes approximately 10 minutes.  Discomfort is minimal and brief – most patients compare the sensation to a bug bite.  You may resume normal activity immediately.

Visible results can last up to 4 months.
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Important Safety Information:

Patients with certain neurological disorders such as ALS, myasthenia gravis, or Lambert-Eaton syndrome may be at increased risk of serious side effects.  Serious allergic reactions have been rarely reported.  If you think you are having an allergic reaction or other unusual symptoms such as difficulty swallowing, speaking, or breathing, call your doctor immediately.  The most common side effects following injection include headache, respiratory infection, flu syndrome, temporary eyelid droop, and nausea.  As your physician if you have any unanswered questions.

Frequently Asked Questions about Restylane® – Immediate and Long-Lasting Wrinkle Correction:

Lady after Restylane Procedure
Lady after Restylane Picture

What is Restylane®?

Restylane® is a safe and natural cosmetic dermal filler that restores volume and fullness to the skin to correct moderate to severe facial wrinkles and folds, such as nasolabial folds.

What is Restylane® made of?

Restylane® is the first cosmetic dermal filler made of non-animal-based hyaluronic acid.  Hyaluronic acid is a natural substance that already exists in the human body and is used to provide volume and fullness to the skin. 

How is Restylane® different than other hyaluronic acid-based products?

Unlike rooster-derived hyaluronic acid-based products, Restylane® is free from animal proteins.  This quality limits any risk of animal-based disease transmission or allergic reaction.

Is Restylane® safe?

Yes.  Restylane® has been used by dermatologists and plastic surgeons since 1996 worldwide.  There is limited risk of animal-based disease transmission or allergic reaction.  Restylane® is fully biocompatible and allergy testing is not required.

Can Restylane® be used anywhere on the face?

Restylane® has been used in more than 1.5 million treatments in over 60 countries to correct a variety of wrinkles.  In the U.S. the FDA has approved Restylane® for wrinkles and folds like the ones from the nose to the corners of the mouth.  Your doctor will consult with you prior to your injection regarding common treatment areas.

How long does Restylane® last?

Restylane® is proven to deliver long-lasting results.  Studies have shown that Restylane® effects generally last for about six months!  Restylane® stabilization technology helps maintain the cosmetic effect until the injected material is nearly gone.

How often should I have Restylane® treatments done?

Treatments are typically scheduled twice a year.  Having a touch-up treatment before the product has fully dissipated may enhance the lasting effect.

What should patients do prior to treatment?

Restylane® requires no pretesting, but you should take a few precautions before being treated.  Avoid using aspirin, non-steroidal anti-inflammatory medications, St. John’s Wort, or high doses of Vitamin E supplements prior to treatment, because these may increase bruising or bleeding at the injection site.  Also, if you have previously suffered from facial cold sores, discuss this with your physician.  He/She may consider prescribing a medication to minimize recurrence.

Do the injections hurt?

Restylane® is injected directly into the skin in tiny amounts by an ultrafine needle, resulting in minimal discomfort.  The procedure is simple and convenient, and results are practically instantaneous.  To optimize your comfort during the short procedure, your physician may anesthetize the treatment area.

How much do Restylane® treatments cost?

Restylane® is a customized procedure based on your specific needs, so the cost will vary from patient to patient.  In general, the cost of Restylane® is comparable to the cost of similar procedures.  Because Restylane® is long lasting, it proves to be very economical over the long term.

Safety Information

After your treatment, you might have some redness or swelling.  This will normally last less than seven days.  Sunbathing and cold outdoors activities should be avoided until any redness or swelling disappear.  If you are pregnant, breastfeeding, or under 18, you should not use Restylane.